In the Bible, Mark 9:43-48, Jesus used startling language to stress the importance of cutting sin out of our lives. Painful discipline is required of his true followers. Giving up a relationship, job, or habit that is against God’s will may seem just as painful as cutting off a hand. Our high goal, however, is worth any sacrifice; Christ is worth any possible loss. Nothing should stand in the way of faith. We must be ruthless in removing sins from our lives. Make your choices from an eternal perspective.
Commentary from the One Year NIV Devotional NT, April 17. Tyndale House Publishers (2003).